Proteins for Immunotherapy Research & Clinical Manufacturing: R&D Systems

Find Your Immunotherapy Proteins

GMP Cytokines
and Growth Factors

GMP

Avi-tag and
Amine Labeled Proteins

Biotinylated

Immune Checkpoint
Proteins and Enzymes

Immune Checkpoint

Cynomolgus and
Rhesus Proteins

NHP

Custom Protein
Development

Custom

Bulk Protein
Requests

Bulk

The immune system plays a key role in the recognition and destruction of cancerous cells. Utilizing and enhancing these properties lies at the heart of immunotherapy. Immune checkpoint therapies that target immuno-suppressive proteins such as PD-1, PD-L1 and CTLA4 have led to transformative new treatments for cancer. Purified versions of the proteins are critical for the development of antibodies, drug screening, and quality control assay development. In addition, novel proteins will help define the next generation of Immunotherapy targets.

Good Manufacturing Practices (GMP)-grade Proteins

High-quality raw materials and ancillary reagents are needed for ex vivo cell manufacturing processes. View our GMP protein portfolio.

Biotinylated Proteins: Avi-tag and Amine Biotinylation

R&D Systems offers an expanding line of Avi-tag and amine-labeled biotinylated proteins. QC tested for equivalent bioactivity and lot-to-lot consistency.

Immune Checkpoint Proteins and Enzymes

Popular Immune Checkpoint proteins

PD-1	PD-L1
CTLA-4	CD28
TIGIT	CD155/PVR
SIRP alpha	CD47
4-1BB	4-1BB Ligand
B7-1	B7-2
LAG-3	Galectin-9
CD40	CD40 Ligand
ICOS	VISTA/B7-H5

Next Generation Immune Checkpoint Proteins

Siglecs	VSTMs
Butyrophilins	VSIGs
CEACAMs	LILRA/B

NEW! Fluorescent-labeled Proteins

Simplify your CAR validation workflow. Bioactive CD19, BCMA, and more conjugated to fluorescent Atto dyes ideal for evaluating CAR expression. Our Fluorescent-labeled proteins are tested using stringent QC standards to ensure consistent labeling while maintaining binding activity and come in a ready to use liquid format eliminating the need for reconstitution. Learn more.

Cynomolgus and Rhesus Proteins

R&D Systems has over 80 cynomolgus and rhesus proteins specifically targeting the Immunotherapy research field.

Custom Protein Development

Utilize our expertise in protein expression, cell culture, protein purification, conjugation, and formulation to create an optimized protein of your choice.